Stephanie Hicks, PhD, was awarded a K99/R00 grant award (NIH Pathway to Independence Award) from National Human Genome Research Institute (NHGRI) for her project, Statistical Methods for the Normalization and Quantification of Single-Cell RNA-Sequencing Data.
Congratulations to Marieke Kuijjer on being a 2016 award recipient of the Sara Elizabeth O'Brien Trust Postdoctoral Research Fellowship for her project "Modeling the Effects of Gene Regulation on Cancer Survival".
Anil Aktas Samur has been awarded ASH Abstract Achievement Award for her abstract titled "A Detailed Alternate Splicing Landscape in Multiple Myeloma with Significant Potential Biological and Clinical Implications" by American Society of Hematology.
Wanling Xie gave an oral presentation at the ESMO 2016 Congress, Oct 7-12, Copenhagen, Denmark. Metastasis free survival is a surrogate for overall survival in localized prostate cancer.
Congratulations to the following people who were promoted on 10/1! James Lindsay, Robert Redd, Bhupendra Rawal, Simon Maisel, Nicole Flanagan, Love Nickerson, Paul Guimond, Shawn Mims, and James Volcker
The following department members received Bonus Awards for 2016: Shuli Li, Linda Christie, Anne O’Neill, Elizabeth Castro-Diaz, Ethan Cerami, Kristen Stevenson, and Nicole Trotman. Congratulations to all!
Marieke Kuijjer was selected as 2016 Awardee through the Charles A. King Trust Postdoctoral Research Fellowship Program. Her project is “Modeling the Effects of Gene Regulation on Cancer Survival”."
Giovanni Parmigiani was awarded the 2016 Junior Faculty Mentoring Achievement Award at the Harvard TH Chan School of Public Health in recognition of his support of young scholars in their intellectual and professional development.
Suzanne Dahlberg was announced as a member of the Lungevity Foundation's Scientific Advisory Board.
Rafa Irizarry's grant "Preprocessing and Analysis Tools for High-Throughput Technologies" was awarded.
John Quackenbush was awarded the 2016 Postdoctoral and Graduate Student Association (PGA) Mentor of the Year
Meredith Regan was invited as Biostatistician Course Director for the AACR/ASCO Methods in Clinical Cancer Research Workshop for 2017-2019.
Rafa Irizarry is in the July 1 New York Times article: "Growing Pains for Field of Epigenetics as Some Call for Overhaul"
Marieke Kuijjer won the Brain Cancer SPORE Career Enhancement Project (CEP) Award for the project "Modeling the effects of gene regulation on glioblastoma development and progression".
Giovanni Parmigiani was profiled in DFCI's Inside the Institute this month, in tribute to his work as department chair for the past 7 years.
Joseph Paulson had two patents accepted: Systems and methods for identifying and flagging samples of concern; S Kamalakaran, JN Paulson; EP Patent WO 2016051298A1 and Systems and methods for tracking and identifying infection transmission; S Kamalakaran, JN Paulson; EP Patent WO 2016024213A3
Ayshwarya Subramanian won a Broadnext10 round 3 Catalytic Steps award, an innovative round of funding instituted by the Broad Institute for independent, catalytic ideas by trainees.
MatchMiner (submitted by Ethan Cerami and the Knowledge Systems Group) won 1st place in the Harvard Precision Trials Challenge
Suzanne Dahlberg is the recipient of the 2016 ECOG-ACRIN Young Investigator Award, one of ECOG-ACRIN’s highest distinctions.
Congratulations to all department members who received Service Awards this year! Linda Christie, Jean Ryan (35 years), Anne O'Neill (20 years), Erica Feick, Keith LeFace (15 years), Renee Rubio, John Quackenbush, Aedin Culhane, Shuli Li, Annie Ng, Wanling Xie, Kristen Stevenson (10 years), Emanuele Mazzola, Fengmin Zhao, Su-Chun Cheng, Jane Craycroft, Natalie Venkskus, Fieda Abderazzaq, Lev Kutnetsov, Luca Pinello, Chongzhi Zang (5 years).
The NIH Big Data to Knowledge (BD2K) T32 Training Grant was funded and will support six PhD students in Biostatistics and Computer Science as they take courses and conduct research focused on the use of Big Data to address important issues in health and biomedical research. John Quackenbush serves as the PI; Francesca Dominici, Rafa Irizarry, Xihong Lin, and David Parkes, Area Dean of Computer Science in the Harvard John A Paulson School of Engineering and Applied Sciences, serve as Associate Directors.
How Can Bioinformatics Help Advance Precision Cancer Care?, an article featuring Chris Sander and Ethan Cerami.
Laura Cava Northrop was promoted to Project Manager II as of June 1st.
Shirley Liu received the Richard E. Weitzman Outstanding Early Career Investigator award from the Endocrine Society
Franziska Michor was awarded the 36th Annual AACR Award for Outstanding Achievement in Cancer Research at the annual meeting this month.
Chris Sander and Ethan Cerami are featured in Inside the Institute this month.
Ethan Cerami's Knowledge Systems Group's new relationship with Intel was published in Fortune.com (http://fortune.com/2016/03/31/intel-cancer-cloud-research/ )
Wanling Xie gave an oral presentation "Disease free survival as an intermediate clinical endpoint for overall survival in patients with localized prostate cancer" at the FDA Hematology and Oncology group meeting.
Shuli Li and Emanuele Mazzola were promoted to Research Scientists as of 3/1/16.
The results from SOFT (Suppression of Ovarian Function Trial) are highlighted by ASCO as a major Clinical Cancer Advance in their 2016 Annual Report on Progress Against Cancer. Meredith Regan is the SOFT trial statistician and co-first author on the NEJM paper cited in the report (http://www.cancerprogress.net/cca/clinical-cancer-advances-2016).
Connie Barysauskas presented a poster at the ASCO Quality Care Symposium in Phoenix AZ; http://meetinglibrary.asco.org/content/160810-181
Judi Manola co-wrote a chapter in UICC Manual of Clinical Oncology, 9th Edition, published last year: http://www.wiley.com/WileyCDA/WileyTitle/productCd-1444332449.html
Keegan Korthauer received a travel award from the Biometrics Section of the ASA to present at JSM 2016 as part of their Young Investigator paper competition. Details of the award here.
Suzanne Dahlberg co-authored this paper which was featured on DFCI Online (only accessable to DFCI employees).
Wanling Xie is lead statistician for GU ASCO oral presentation: Discontinuing VEGF-targeted therapy (VEGF-TT) for progression versus toxicity impacts outcomes of second-line therapies in metastatic renal cell carcinoma (mRCC).
Shirley Liu succeeded Rafa Irizarry as the Chair of the NIH Genomics, Computational Biology and Technology (GCAT) Study Section.
Meredith Regan is the new Co-Chair of the Committee for Women Faculty at Dana-Farber.
February 2016 Promotions: Elizabeth Castro-Diaz was promoted to Administrative Support Specialist II, Jean Ryan was promoted to Program Administrator II, Erica Feick was promoted to Program Administrator III
Franziska Michor receives the 2015 New York Stem Cell Foundation – Robertson Stem Cell Prize Recipient (http://nyscf.org/grants/nyscf-robertson-prize)
Ayshwarya Subramanian's poster received a Stellar Abstract Award at the 2015 Program in Quantitative Genomics (PQG) Conference on "Single-Cell Genomics" held at Nov 5-6, 2015 at HMS.
Anita Giobbie-Hurder gave two presentations at SABCS 2015: (Poster Discussion) Cholesterol, Cholesterol Lowering Medication Use, and Breast Cancer Outcomes in the BIG 1-98 Study; (Poster): PANACEA (IBCSG 45-13/BIG 4-13): Phase Ib/II Trial Evaluating the Efficacy of Pembrolizumab and Trastuzumab in Patients with Trastuzumab-resistant, HER2-positive, Metastatic Breast Cancer.
During a “hackathon” at the Blackfan campus on Dec. 7 and 8, representatives from four institutions brainstormed and developed new features for the cBioPortal– a web-based system for viewing and analyzing the genomic data from thousands of cancer patients. In addition to Dana-Farber's Ethan Cerami, PhD, James Lindsay, PhD, and Priti Kumari, the event drew attendees from Memorial Sloan Kettering Cancer Center (MSK), the Princess Margaret Cancer Centre in Toronto, and The Hyve – an open-source bioinformatics company headquartered in the Netherlands.
Bob Gray and the TAILORx trials has garnered a lot of new attention lately! Here are a few links:
Aedin Culhane gave invited talks at iBright, MD Anderson http://www.mdanderson.org/education-and-research/departments-programs-and-labs/departments-and-divisions/division-of-quantitative-sciences/educational-programs/ibright-2015.html; EARL (Effective Applications of the R Language), http://www.earl-conference.com/boston/; and BioStatNet Workshop on Biomedical Big Data,Centre de Recerca Matemàtica, CRM, Barcelona, http://www.crm.cat/en/Activities/Curs_2015-2016/Pages/Biostatnet2015.aspx
Stephanie Hicks was selected as a Stellar Abstract Award winner and presented a short platform talk at the 2015 Program in Quantitative Genomics (PQG) Conference held at Harvard Medical School Nov 5-6, 2015.
Scott Carter and his colleagues work in charting the 'genomic biography' of form of leukemia was featured in the American Association for the Advancement of Science (AAAS) EurekAlert on October 14th. http://www.eurekalert.org/pub_releases/2015-10/dci-sc100915.php
Wei Li's recent work (a joint work with Johannes Koster), "Quality control, modeling and visualization of genome-wide CRISPR screens using MAGeCK-VISPR" was given an oral presentation at the CSHL meeting, "Genome Engineering: The CRISPR/Cas9 Revolution".https://meetings.cshl.edu/abstracts.aspx?meet=CRISPR&year=15
Anne O'Neill was the first author and gave a poster presentation at Global Cardio Oncology Summit in Nashville, TN on Ocotber 14-16 for the ECOG-ACRIN Cardiotoxicity Working Group.
Promotions for October 2015 - congratulations!
Hao Guo, Traci Blonquist, and Connie Barysauskas to MS Statistician II
Ju-Whei Lee and Yu-Hui Chen to MS Statistician III
Research by Guo-Cheng Yuan, Luca Pinello (co-first author), and Sara Garcia on gene-editing approaches to treating sickle cell disease is featured in the September 16 Harvard Gazette. http://news.harvard.edu/gazette/story/2015/09/achilles-heel-of-sickle-cell-disease
Suzanne Dahlberg was invited to speak at the Expansion Cohort Mini-Symposium at the FDA on September 10. Dr. Dahlberg is also the lead statistician for one study (1) presented in the plenary session and two studies presented in oral sessions (2,3) at the 16th World Conference on Lung Cancer.
Mehmet Samur, David Mosen-Ansorena, and Alice Cleynen were invited to present multiple oral presentations and posters at this year's ASH meeting.
Aedin Culhane co-presented a workshop with Levi Waldron and Tim Triche on integrative analysis of multi-omic data sets at the annual Bioconductor conference, Bioc 2015, in Seattle (http://bioconductor.org/help/course-materials/2015/BioC2015/)
Meredith Regan was in Vail, Colorado as faculty at the ASCO/AACR Methods in Clinical Cancer Research Workshop. The week-long workshop educates clinical fellows and junior faculty clinical researchers in all oncology subspecialties about the essentials of effective clinical trial designs of therapeutic interventions in the treatment of cancer. This is her eighth year as faculty. (http://www.aacr.org/Meetings/Pages/MeetingDetail.aspx?EventItemID=51#.Vbo4YvnrMo0)
Congratulations to Hua-Jun Wu and Jiantao Shi for their recent promotions to Research Associate.
John Quackenbush was featured in the Boston Globe for participating in the Haymakers for Hope charity fundraiser. John raised over $30,000 for junior faculty support in our department in his May 14th bout.
Franziska Michor was promoted to tenured professor of computational biology in the Department of Biostatistics at the Harvard T.H. Chan School of Public Health, as well as in the Department of Biostatistics and Computational Biology at the Dana-Farber Cancer Institute. She is also the new Leader of the Biostatistics and Computational Biology Program for the Dana-Farber/Harvard Cancer Center.
Fengmin Zhao's co-authored paper on neuropathy in colorectal cancer and Meredith Regan's co-first author NEJM paper on the TEXT and SOFT trials are featured in the March 25 edition of the ASCO Post.
Meredith Regan is featured in ASCO Connection's 2015 Trainee and Early Career Oncologists issue: "Career Journeys: Meet Statistician Meredith M. Regan, ScD."
Haesook Kim was the Invited speaker at the joint annual meeting of American Society for Blood and Marrow Transplantation (ASBMT) and the Center for International Blood and Marrow Transplant Research (CIBMTR) in San Diego, CA earlier this month. Her talk title was "Clinical Endpoints in Allogeneic Hematopoietic Stem Cell Transplantation"
Rafa Irizarry is profiled as "one of America's most influential scientists" in the Feb. 26 issue of Puerto Rican newspaper El Nuevo Día.
Ethan Cerami's "OncoBlocks” project was accepted for Google Summer of Code: 2015, a Google program offering student developers stipends to write code for various open source software projects. OncoBlocks aims to create reusable, open source software components to support cancer genomics research and enable precision cancer medicine.
Meredith Regan, Richard Gelber, and Anita Giobbie-Hurder are featured in an Inside the Institute article about the SOFT/TEXT trials.
Franziska Michor won a 2015 Vilcek Prize for Creative Promise in Biomedical Sciences. The Vilcek Prizes for Creative Promise encourage and support young immigrants who have already demonstrated exceptional achievements and who often face significant challenges early in their careers.
Dr. Rafael Irizarry is quoted in the Boston Globe article about the Joint Statistical Meetings in Boston.
Bioconductor 2014 Conference is held at Dana-Farber July 30-August 1; the first time the conferece has come to the East Coast.
Dr. John Quackenbush is quoted in an LA Times article about genomics and a recent paper in Cell.
Dr. Rafael Irizarry is recognized by Thomson Reuters as one of the "world's most influential scientific minds" in 2014.
Practice-changing clinical research led by Meredith Regan, Robert Gray, Yu-Hui Chen and Richard Gelber highlighted in ASCO 2014 Annual Meeting Plenary Session.
Suzanne Dahlberg is promoted to Senior Research Scientist. Congratulations Suzanne!
John Quackenbush gives the keynote address at Bio-IT World 2014.
Franziska Michor is featured in Nature Medicine.
Congratulations to Jean Ryan, for winning the Dana-Farber Administrative Professional's Award!
"New radiotherapy treatment schedule shows promise in brain cancer"; Franziska Michor is highlighted in Inside the Institute.
John Quackenbush was interviewed by CBS Boston on the Future of Boston: Leading the Way in Biotech Research.
Fangxin Hong is promoted to Senior Research Scientist. Congratulations Fangxin!
John Quackenbush is part of an article on "Why Big Data is a Big Deal" in Harvard Magazine.
Kimberly Glass won a $50,000 Fellowship from the Geoffrey Been Foundation in the 2013 Global NeuroDiscovery Challenge for her proposal to study sexual dimorphism in Alzhiemer's.
A study led by Dr. Suzanne Dahlberg shows lung cancer outcomes are better in obese patients early on, but obesity is linked to
an overall higher risk of death.
Rafael Irizarry has joined the Department as a Professor of Biostatistics. He is the winner of the COPPS, is one of the most cited statisticians of all times, and is also a master at communicating complex bioinformatics ideas to students of all backgrounds, and one of the major movers in opens source software.
Haesook Kim is promoted to Principal Research Scientist and Svitlana Tyekucheva is promoted to Research Scientist. Congratulations Haesook and Svitlana!
John Quackenbush is honored at the White House as an Open Science Champion of Change.
Erica Feick was the recipient of the Institute's Annual Administrative Professional Award. See more pictures here.
Guo-Cheng Yuan was promoted to Associate Professor at the Harvard School of Public Health. Congratulations GC!
Franziska Michor discussed Evolution and Cancer in the Fall/Winter Paths of Progress.
William Barry, formerly of Duke University, joined the Department to work with physician-scientists in DFCI’s Susan F. Smith Center for Women’s Cancers. Barry is the first Nancy and Morris John Lurie Investigator, made possible by a gift from the CJL Foundation, with support from members of the Susan F. Smith Center Visiting Committee.
Marvin Zelen was awarded the Karl E Peace Award from the ASA for Outstanding Statistical Contributions for the Betterment of Society. The award was conferred at the 2012 JSM Meeting.
Xiaole Liu was promoted to Professor at the Harvard School of Public Health. Congratulations!
Franziska Michor spoke at TEDMED on Evolution and Cancer.
John Quackenbush's book The Human Genome was published. The book takes the reader on a tour of the history and science behind the Human Genome Project and the technologies that are revolutionizing the practice of medicine today.
Franziska Michor and the PS-OC were highlighted on DFCI Online: Center focuses on the physics of cancer
Interview with John Quackenbush, Kimberly Glass and Megha Padi; How physics found a home in cancer biology, DFCI Online
Richard Gelber was awarded the ECCO Clinical Research Award for his outstanding work in breast cancer research. This prestigious award is given in recognition of an outstanding international contribution to the integration of scientific research and clinical practice in the field of cancer.
Mick Correll was awarded the the Excellence in Management Award from the Institute for his work for the CCCB.
Jim Volcker was named Dana-Farber Cancer Institute's 2011 Employee of Year. Congratulations Jim! Pictures from the ceremony can be viewed here (internal only).