Rebecca Gelman

Associate Professor
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Research


Rebecca Gelman is involved in collaborative research on cancer and AIDS. She is coordinator of biostatistics collaboration at the Dana-Farber Cancer Institute, where she primarily works on breast cancer clinical trials, breast cancer screening studies, pathology studies, tumor marker studies, and immunogenetics. She is the coordinating statistician for the Harvard Collaborative Oncology Group, which involves cancer clinical trials and epidemiology studies at eight hospitals.

 

Her primary appointment is in the Radiation Oncology department of Harvard Medical School, where she works on breast cancer, prostate cancer and multiple myeloma studies. Dr. Gelman is section head for the Immunology Committee of the AIDS Clinical Trial Group, and serves on the Flow Advisory Committee of the NIAID. She works on clinical trials of immune-based therapies, runs the national program on flow cytometry quality assessment, and does research on the sources of variation and prognostic/surrog! ate value of immunology tests.

 

Dr. Gelman's statistical interests reflect her collaborative activities. She is currently involved in:

  1. proposing new methods for analysis of cancer screening trials,
  2. quantitating the value of quality assessment programs in prognostic and surrogate factor studies,
  3. comparing different methods of estimating confidence intervals for coefficient of variation, and
  4. developing competing risk models for long-term effects of chemotherapy and radiation.

 

Biography

Dr. Gelman received her PhD in statistics from the State University of New York, Buffalo, in 1978. In the same year, she joined the Department of Biostatistics at Harvard School of Public Health and DFCI, and in 1990, the Department of Radiation Oncology at Harvard Medical School. She is associate director of the Biostatistics Core of the Dana-Farber/Harvard Cancer Center, principal investigator of the Biostatistics Core of the Harvard Center for AIDS Research, and chief statistician for the National Institute of Allergy and Infectious Diseases (NIAID) Division of AIDS Immunology Laboratory Quality Assessment Program. She is the only statistician member of the Flow Advisory Committee to the NIAID.

 

Recent Publications

Ibrahim M, Moyo S, Mohammed T, Mupfumi L, Gaseitsiwe S, Maswabi K, Ajibola G, Gelman R, Batlang O, Sakoi M, Auletta-Young C, Makhema J, Lockman S, Shapiro RL. High Sensitivity and Specificity of the Cepheid Xpert® HIV-1 Qualitative Point-of-Care Test among Newborns in Botswana. J Acquir Immune Defic Syndr. 2017 Mar 24.

 

Ojikutu BO, Mazzola E, Fullem A, Vega R, Landers S, Gelman RS, Bogart LM. HIV
Testing Among Black and Hispanic Immigrants in the United States. AIDS Patient
Care STDS. 2016 Jul;30(7):307-14.

 

Wang H, Bierie B, Li AG, Pathania S, Toomire K, Dimitrov SD, Liu B, Gelman R,
Giobbie-Hurder A, Feunteun J, Polyak K, Livingston DM. BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells. Mol Cell. 2016 Jul 21;63(2):277-92.

 

Freedman RA, Gelman RS, Wefel JS, Melisko ME, Hess KR, Connolly RM, Van Poznak CH, Niravath PA, Puhalla SL, Ibrahim N, Blackwell KL, Moy B, Herold C, Liu MC, Lowe A, Agar NY, Ryabin N, Farooq S, Lawler E, Rimawi MF, Krop IE, Wolff AC, Winer EP, Lin NU. Translational Breast Cancer Research Consortium (TBCRC) 022: A Phase II Trial of Neratinib for Patients With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases. J Clin Oncol. 2016 Mar 20;34(9):945-52.

 

Nakhlis F, Gilmore L, Gelman R, Bedrosian I, Ludwig K, Hwang ES, Willey S,
Hudis C, Iglehart JD, Lawler E, Ryabin NY, Golshan M, Schnitt SJ, King TA.
Incidence of Adjacent Synchronous Invasive Carcinoma and/or Ductal Carcinoma
In-situ in Patients with Lobular Neoplasia on Core Biopsy: Results from a
Prospective Multi-Institutional Registry (TBCRC 020). Ann Surg Oncol. 2016
Mar;23(3):722-8.

 

Walter JE, Rosen LB, Csomos K, Rosenberg JM, Mathew D, Keszei M, Ujhazi B,
Chen K, Lee YN, Tirosh I, Dobbs K, Al-Herz W, Cowan MJ, Puck J, Bleesing JJ,
Grimley MS, Malech H, De Ravin SS, Gennery AR, Abraham RS, Joshi AY, Boyce TG, Butte MJ, Nadeau KC, Balboni I, Sullivan KE, Akhter J, Adeli M, El-Feky RA,
El-Ghoneimy DH, Dbaibo G, Wakim R, Azzari C, Palma P, Cancrini C, Capuder K,
Condino-Neto A, Costa-Carvalho BT, Oliveira JB, Roifman C, Buchbinder D,
Kumanovics A, Franco JL, Niehues T, Schuetz C, Kuijpers T, Yee C, Chou J, Masaad MJ, Geha R, Uzel G, Gelman R, Holland SM, Recher M, Utz PJ, Browne SK, Notarangelo LD. Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency. J Clin Invest. 2015 Nov 2;125(11):4135-48.

 

Gombos RB, Kolodkin-Gal D, Eslamizar L, Owuor JO, Mazzola E, Gonzalez AM,
Korioth-Schmitz B, Gelman RS, Montefiori DC, Haynes BF, Schmitz JE. Inhibitory
Effect of Individual or Combinations of Broadly Neutralizing Antibodies and
Antiviral Reagents against Cell-Free and Cell-to-Cell HIV-1 Transmission. J
Virol. 2015 Aug;89(15):7813-28.

 

Mandala WL, Ananworanich J, Apornpong T, Kerr SJ, MacLennan JM, Hanson C,
Jaimulwong T, Gondwe EN, Rosenblatt HM, Bunupuradah T, Molyneux ME, Spector SA, Pancharoen C, Gelman RS, MacLennan CA, Shearer WT. Control lymphocyte subsets: can one country's values serve for another's? J Allergy Clin Immunol. 2014 Sep;134(3):759-761.e8.

 

Wong JS, Chen YH, Gadd MA, Gelman R, Lester SC, Schnitt SJ, Sgroi DC, Silver
BJ, Smith BL, Troyan SL, Harris JR. Eight-year update of a prospective study of
wide excision alone for small low- or intermediate-grade ductal carcinoma in situ
(DCIS). Breast Cancer Res Treat. 2014 Jan;143(2):343-50.

 

Walter JE, Rosen LB, Csomos K, Rosenberg JM, Mathew D, Keszei M, Ujhazi B,
Chen K, Lee YN, Tirosh I, Dobbs K, Al-Herz W, Cowan MJ, Puck J, Bleesing JJ,
Grimley MS, Malech H, De Ravin SS, Gennery AR, Abraham RS, Joshi AY, Boyce TG, Butte MJ, Nadeau KC, Balboni I, Sullivan KE, Akhter J, Adeli M, El-Feky RA,
El-Ghoneimy DH, Dbaibo G, Wakim R, Azzari C, Palma P, Cancrini C, Capuder K,
Condino-Neto A, Costa-Carvalho BT, Oliveira JB, Roifman C, Buchbinder D,
Kumanovics A, Franco JL, Niehues T, Schuetz C, Kuijpers T, Yee C, Chou J, Masaad MJ, Geha R, Uzel G, Gelman R, Holland SM, Recher M, Utz PJ, Browne SK, Notarangelo LD. Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency. J Clin Invest. 2016 Nov 1;126(11):4389.

 

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