• 617-632-3012
  • This email address is being protected from spambots. You need JavaScript enabled to view it.

DFCI/FSTRF Marvin Zelen Memorial Symposium

The Dana-Farber Cancer Institute/Frontier Science Technology and Research Foundation Annual Lecture was renamed the Marvin Zelen Memorial Symposium in 2016, in honor of Dr. Zelen's contributions to science and cancer research. Marvin Zelen was known as a giant in the field of biostatistics, as well as a man of vision, generosity, and warmth who served as a mentor to two generations of researchers. 

2018 Symposium

The 2018 symposium will be held on Friday April 6, 2018 at the Dana-Farber Cancer Institute. Speakers will be announced shortly. 

Previous Symposiums

Contemporary Statistical Challenges in Clinical Research

April 7, 2017

Boston Red Sox Jimmy Fund Auditorium, Dana-Farber Cancer Institute

A special tribute in honor of Richard Gelber on his 70th Birthday.

  • Gather, Welcome & Introduce Speakers - Meredith Regan, Associate Professor, Harvard Medical School, Dana-Farber Cancer Institute
  • Eleanor McFadden, Managing Director, Frontier Science (Scotland), Ltd., International Trials and Tribulations
  • Alan Coates, Clinical Professor, School of Public Health, the University of Sydney, Biostatistics at the Clinical Interface: Quality of Life as a Prognostic Factor
  • Aron Goldhirsch,Deputy Scientific Director of the European Institute of Oncology (IEO), Milan, Italy, Challenges in Clinical Research: Focus on Breast Cancer
  • Michael Hughes,Professor of Biostatistics, Director, Center for Biostatistics in AIDS Research, Harvard TH Chan School of Public Health, A Brief History of Statistical Issues in Research to Reduce Mother-to-Child HIV Transmission
  • Bernard Cole,Professor of Statistics and Statistics Program Director, Department of Mathematics and Statistics, University of Vermont, Evaluating Treatment-Effect Heterogeneity in the Age of Biomarkers: Subpopulation Treatment Effect Pattern Plot (STEPP)
  • Lee-Jen Wei,Professor of Biostatistics, Harvard TH Chan School of Public Health, The Myth of Design and Analysis of Cancer Clinical Studies with PFS or OS as the Endpoint
  • Cyrus Mehta,  Adjunct Professor of Biostatistics, Harvard TH Chan School of Public Health and President, Cytel Software Corporation, Adaptive Designs for Confirmatory Clinical Trials
  • Colin Begg,  Chairman and Attending Biostatistician, Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, Complexities in the Design of Basket Clinical Trials of Targeted Agents
  • Richard Gelber, Professor of Biostatistics, Harvard TH Chan School of Public Health, Harvard Medical School, Dana-Farber Cancer Institute
  • Closing Remarks - Meredith Regan

This lecture is sponsored by Frontier Science Technology and Research Foundation.

Clinical Trials in the Era of Precision Medicine

April 1, 2016
Boston Red Sox Jimmy Fund Auditorium, Dana-Farber Cancer Institute


  • Lisa McShane, Precision Medicine: Promise, Innovation, Trials and Tribulations
  • Williams Sellers, Developing the Next-Generation of Cancer Therapeutics
  • D. Neil Hayes, Precision Medicine for Patients with Advanced Cancer: Basket trials, Bucket trials, Off Label Therapies and Other Outcomes
  • Eli Van Allen, Clinical Computational Oncology for Precision Cancer Medicine
  • Meredith Regan, Biomarker-Driven Trials in the International Breast Cancer Study Group
  • Robert Gray, The NCI MATCH Trial
  • Lorenzo Trippa, Bayesian Baskets: A Design for Biomarker-Based Clinical Trials
  • 2014: Lisa LaVange, The Role of Statistics in Regulatory Decision Making
  • 2013: Margaret Pepe, Evaluating Improvement in Risk Prediction Gained with Use of a New Marker
  • 2012: John Storey, Statistical Challenges in the Analysis of Clinical Genomics Studies
  • 2011: Keith Baggerly, The Importance of Reproducible Research in High-Throughput Biology: Case Studies in Forensic Bioinformatics
  • 2010: Donald Berry, The Screening Mammography Brouhahas and Adaptive Clinical Trials
  • 2009: Terry Speed, Statisticians, omic data and therapeutic strategies to treat cancer
  • 2008: Albert-Laszlo Barabasi, Network Medicine: From the Human Diseasome to Comorbodity Patterns
  • 2005: Albert-Laszlo Barabasi, Network Biology: From Metabolic to Protein Interaction networks
  • 2004: Alan Coates, p is for Politics: The Link Between Statistical Evidence and Public Policy
  • 2003: Steven Goodman, The Mammography Controversy: A Crisis for Evidence-Based Medicine?
  • 2002: Giovanni Parmigiani, Statistical Issues in Expression Based Molecular Classification of Cancer
  • 2001: Sir Richard Peto, Simple Methods for Meta-Analyses Can Be Statistically Optimal: EBCTCG and PSC
© 2018 All Rights Reserved.