The Department of Biostatistics and Computational Biology
The Department of Biostatistics and Computational Biology combines independent research, collaboration, and consultation in quantitative methods as they apply to cancer, the environment, and research into the acquired immunodeficiency syndrome (AIDS), as well as focusing on the application of functional genomics techniques – including microarrays, proteomics, metabolomics, and other high-throughput approaches – and the development of computational approaches in support of these studies to develop a comprehensive view of human diseases including cancer.
The Department is one of the nation's major statistical centers for carrying out multicenter clinical trials by virtue of being the statistical center of the Eastern Cooperative Oncology Group (ECOG) and the International Breast Cancer Study Group (IBCSG). Members of the Department are working closely with the AIDS Clinical Trial Group (ACTG) by leading the coordination of statistics for pediatric AIDS and immunologic markers for detecting human immunodeficiency virus (HIV) infection. The Biostatistics Core research component is a shared facility that supports consultation on quantitative methods throughout the Dana-Farber/Harvard Comprehensive Cancer Center (DF/HCC).
The Department is also home to the Computational Biology and Functional Genomic Lab, which focuses on the application of functional genomics techniques–including microarrays, proteomics, metabolomics, and other high-throughput approaches–and the development of computational approaches in support of these studies to develop a comprehensive view of human diseases including cancer, as well as the Center for Cancer Computational Biology(CCCB), which provides broad-based support for the generation, analysis and interpretation of ‘omic data, furthering basic, clinical, and translational research.
The department has a close partnership with the Department of Biostatistics at Harvard School of Public Health, where the majority of our faculty hold primary academic appointments.
